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Identifiant d'origine
QD446
Note de contenu Q-Code
Contenu conceptuel Q-Code
Futile medical treatment ; Treatment that is usually considered unable to produce the desired benefit either because it cannot achieve its physiological aim or because the burdens of the treatment are considered to outweigh the benefits for the particular individual. There are necessary value judgements involved in coming to an assessment of futility. These judgements must consider the individual’s, or proxy’s, assessment of worthwhile outcome. (WHOGloss2004)
Medical Futility ; The absence of a useful purpose or useful result in a diagnostic procedure or therapeutic intervention. The situation of a patient whose condition will not be improved by treatment or instances in which treatment preserves permanent unconsciousness or cannot end dependence on intensive medical care. (From Ann Intern Med 1990 Jun 15;112(12):949)(MeSH)
Number Needed to Harm ; The number of people who would need to be treated over a specific period of time before one bad outcome of the treatment will occur. The number needed to harm (NNH) for a treatment can be known only if clinical trials of the treatment have been performed.(AHRQ)
Number Needed to Treat ; The number of people who need to be treated over a specific period of time to promote one additional good outcome (or prevent one additional bad outcome). The number needed to treat (NNT) for a treatment can be known only if clinical trials of the treatment have been performed.(AHRQ)
overtreatment; an excessive drug load leading to a suboptimal risk-to-benefit ratio. Initiating treatment in conditions where it is not indicated. Use of excessively fast titration rates. Prescription of excessively high initial target dosages. Failure to consider conditions associated with reduced dosage requirements. Failure to consider the dose-response characteristics of the selected drug. Premature use of combination therapy. Failure to adjust the dosage to prevent or compensate for adverse pharmacokinetic or pharmacodynamic drug interactions. Failure to reduce drug load in patients who have not benefited from high dosages or polypharmacy. Continuation of drug therapy in disease-free patients. (Peruka & Kwan 2005)
CUI UMLS
C0242652
Référence bibliographique
Citation
Albarqouni, Loai, et al. "Overuse of medications in low-and middle-income countries: a scoping review." Bulletin of the World Health Organization (2022).
Austad B, Hetlevik I, Mjølstad BP, Helvik AS. Applying clinical guidelines in general practice: a qualitative study of potential complications. BMC family practice. 2016; 17: 92. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27449959
Cuba Fuentes MS, Zegarra Zamalloa CO, Reichert S, Gill D. Attitudes, perceptions and awareness concerning quaternary prevention among family doctors working in the Social Security System, Peru: a cross-sectional descriptive study. Medwave. 2016; 16(3): e6433. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27144838
Jerant A, Kravitz RL, Fernandez Y Garcia E, Feldman MD, Cipri C, Nishio D, Knoepfler A, Wooddell MK, Baquero V, Franks P. Potential antidepressant overtreatment associated with office use of brief depression symptom measures. Journal of the American Board of Family Medicine : JABFM. 2014; 27(5): 611-20. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25201931
Maurer D, Stephens M, Reamy B, Crownover B, Crawford P, Chang T. Response: re: family physicians’ knowledge of commonly overused treatments and tests. Journal of the American Board of Family Medicine : JABFM. 2015; 28(1): 162. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25715437
Mercier A, Auger-Aubin I, Lebeau JP, Van Royen P, Peremans L. Understanding the prescription of antidepressants: a Qualitative study among French GPs. BMC family practice. 2011; 12: 99. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21943348
Perucca E, Kwan P. Overtreatment in epilepsy: how it occurs and how it can be avoided. CNS drugs. 2005; 19(11): 897-908. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16268662
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